Spectrocolorimetric evaluation of human articular cartilage

Spectrocolorimetric Evaluation of Repaired Articular Cartilage in Rabbits

Introduction: In clinical practice, repaired cartilage is often assessed by visual inspection and probing using arthroscopy. Through an arthroscopic monitor, human eyes can differentiate color changes in repaired cartilage compared with surrounding intact cartilage, but cannot quantify these color changes. Therefore, there is a need for an objective method to evaluate the repaired tissue itself...

Electrokinetic evaluation of human articular cartilage

Differential Immunohistochemical Expression Pattern of Galectin-3 in Normal and Osteoarthritic Human Articular Cartilage

Background: Previous studies have shown that Galectin-3, a member of lectin family, is expressed in developing cartilage in mouse embryo and also in growth plate of long bones.   Objective: In the present work, the expression pattern of Galectin-3 in normal and various grades of osteoarthritic (OA) human articular cartilage has been studied.   Methods: Using immunohistochemistry and standard we...

The reactions of injured human articular cartilage.

The physical and chemical structure of normal hyaline articular cartilage was described by Collins (1949), but there is little published on its reactions to injury and repair in the human subject, though animal observations have been made, notably by Bennett, Bauer and Maddock (1932). The slow metabolism and physiological inactivity of joint cartilage were emphasised by Bywaters (1937), again m...

Degradome expression profiling in human articular cartilage

INTRODUCTION The molecular mechanisms underlying cartilage destruction in osteoarthritis are poorly understood. Proteolysis is a key feature in the turnover and degradation of cartilage extracellular matrix where the focus of research has been on the metzincin family of metalloproteinases. However, there is strong evidence to indicate important roles for other catalytic classes of proteases, wi...